Brain trauma elicits non-canonical macrophage activation states
نویسندگان
چکیده
منابع مشابه
Non-visible penetrating brain trauma: a case report
Objective: One of the most frequent causes of death and acquired disability in the pediatric population is the Traumatic Brain Injury (TBI). TBI is secondary to falls, road traffic and vehicle collisions, child abuse and assaults. Penetrating brain injury is a severe form of traumatic brain injury. Blunt head injury is more frequent than TBI in children, but the second one carries a poor progno...
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After traumatic brain lesion, microglial cells are rapidly activated, migrate toward the sites of injury, and cause secondary damage that accounts for most of the loss of brain function. In the present study, we have characterized a new macrophage/microglia activation factor (MAF). Using the monocytic cell line U937, we were able to demonstrate that MAF is upregulated after TPA-induced differen...
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ژورنال
عنوان ژورنال: Journal of Neuroinflammation
سال: 2016
ISSN: 1742-2094
DOI: 10.1186/s12974-016-0581-z